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近年来,环境化学污染增加可看成是遗传疾病的病原因素之一。等报道,工业发达国家的新生儿异常和自发流产数增多,其中许多与染色体损伤有关。等认为,分析接触致突变物的人的淋巴细胞染色体畸变(XA),是直接评价发生突变的最有效方法之一。该法已广泛用于化学物质生产环境的研究,但很少用于研究大气污染不同程度地区的人群。作者采用人末梢血淋巴细胞XA试验,对现代化石油化工企业排出的某些化学物质对居民的致突变作用,并对城市大气污染物致突变
In recent years, the increase of environmental chemical pollution can be regarded as one of the pathogenic factors of genetic diseases. According to other reports, the number of neonatal abnormalities and spontaneous abortion increased in industrialized countries, many of which were related to chromosome damage. And so that the analysis of human exposure to mutants of lymphocyte chromosome aberrations (XA), is a direct evaluation of one of the most effective method of mutation. The law has been widely used in chemical production environment research, but rarely used to study the air pollution in different parts of the population. Using human peripheral blood lymphocyte XA test, the author of the modern petrochemical enterprises discharged some of the chemical substances to residents of the mutagenic effect on urban air pollutants and mutations