雌激素治疗因其能缓解更年期症状和防止骨质疏松而获得广泛应用。虽然骨胶原基质的生物化学与皮肤胶原基本相同,但雌激素与骨和雌激素与皮肤的研究没做过比较。仅有雌激素和睾丸酮对皮肤影响的间接证据。由于皮肤中成纤维细胞有雌激素和雄激素两种受体,作者等观察了雌二醇和睾丸酮对绝经后妇女皮肤的影响。 作者等选择29例未经治疗的绝经期后妇女作为 Estrogen therapy is widely used because of its ability to relieve menopausal symptoms and prevent osteoporosis. Although the biochemistry of collagen matrix is ​​similar to that of skin collagen, no comparison has been made between estrogen and bone and estrogen versus skin studies. Indirect evidence of the effect of estrogen and testosterone alone on the skin. As the skin fibroblasts have two receptors, estrogen and androgen, the authors observed the effects of estradiol and testosterone on the skin of postmenopausal women. The authors chose 29 cases of untreated postmenopausal women as