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目的:观察胺碘酮治疗阵发性快速室上性心律失常的临床疗效及安全性。方法:对23例经心电图确诊为快速室上性心律失常伴器质性心脏病的患者,以胺碘酮150mg用生理盐水稀释至20ml,采用微量注射泵缓慢静脉注射,时间10min、30min后效果不满意依前法可再次静脉注射150mg,如仍无效则以20mg/h静脉滴注维持不超过24h。治疗期间持续心电、血压监测,密切观察疗效及不良反应。结果:显效15例,有效5例,无效3例,总有效率86.96%。用药期间未发生严重不良反应。结论:静脉注射胺碘酮能有效治疗阵发性快速室上性心律失常,尤其是伴器质性心脏病的心律失常,采用缓慢精确的给药方式可以提高疗效并大大减少药物不良反应的发生。
Objective: To observe the clinical efficacy and safety of amiodarone in the treatment of paroxysmal supraventricular arrhythmias. Methods: Twenty-three patients confirmed by electrocardiogram as having rapid supraventricular arrhythmias with organic heart disease were treated with amiodarone (150mg) diluted to 20ml with normal saline and slowly injected intravenously by microinjection pump for 10min and 30min Dissatisfied according to the former law can be intravenous injection of 150mg, if still not effective to 20mg / h intravenous infusion of not more than 24h. Continuous treatment of ECG, blood pressure monitoring, close observation of efficacy and adverse reactions. Results: 15 cases were markedly effective, 5 effective and 3 ineffective, with a total effective rate of 86.96%. Serious adverse reactions did not occur during the treatment. Conclusion: Intravenous amiodarone is effective in treating paroxysmal supraventricular arrhythmias, especially arrhythmia with organic heart disease. The slow and accurate administration can improve the curative effect and greatly reduce the occurrence of adverse drug reactions .