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[摘要] 目的 探讨TACE联合PSE在伴有肝硬化脾功能亢进的原发性肝癌患者介入性治疗上的临床应用价值。方法 58例原发性肝癌伴脾功能亢进的患者均采用TACE和PSE治疗。介入治疗后分别定期复查患者的外周血常规，通过肝脏CT上碘油的沉积范围来评价TACE及PSE术后的疗效。结果 所有肿瘤的体积均变小。所有患者的AFP值术后均有不同程度的下降，其中40例患者（69%）的AFP降到100μg/L之内。所有患者在CT上可见脾脏内大小不等的低密度梗死区，范围为40%～80%。本组病例术后无明显严重的并发症发生。结论 TACE联合PSE在伴有脾功亢进的原发性肝癌患者的治疗上具有较大的临床价值。
[关键词] 原发性肝癌； 脾功能亢进； 经动脉化疗栓塞术； 部分脾动脉栓塞术
[中图分类号] R735.7 [文献标识码] A [文章编号] 1673-9701（2009）13-11-03
Application of TACE and PSE in Treatment of Primary Hepatic Carcinoma with Splenofunction Accentuation
SUN Zhichang SUN Dewen
The Second People’s Hospital in Panjin City，Liaoning 124000
[Abstract] ObjectiveTo explore the clinical value of interventional therapy in primary liver carcinoma patients with splenofunction accentuation by both Transarterial Chemoembolization（TACE） and PSE. MethodsThere are 58 primary liver carcinoma patients with splenofunction accentuation，who had been treated by both TACE and PSE. After the interventional therapies，the blood cells account and the depositive field of iodized oil in CT of all patients had been measured to appraise the curative effects of TACE
[关键词] 原发性肝癌； 脾功能亢进； 经动脉化疗栓塞术； 部分脾动脉栓塞术
[中图分类号] R735.7 [文献标识码] A [文章编号] 1673-9701（2009）13-11-03
Application of TACE and PSE in Treatment of Primary Hepatic Carcinoma with Splenofunction Accentuation
SUN Zhichang SUN Dewen
The Second People’s Hospital in Panjin City，Liaoning 124000
[Abstract] ObjectiveTo explore the clinical value of interventional therapy in primary liver carcinoma patients with splenofunction accentuation by both Transarterial Chemoembolization（TACE） and PSE. MethodsThere are 58 primary liver carcinoma patients with splenofunction accentuation，who had been treated by both TACE and PSE. After the interventional therapies，the blood cells account and the depositive field of iodized oil in CT of all patients had been measured to appraise the curative effects of TACE