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目的:探析十八反甘草药组临床应用规律。方法:检索某省级三甲医院近3年来(2009.11—2012.11)十八反甘草组应用情况,并对其进行分析、归纳和总结。结果:与甘草临床同用频率依次为海藻>醋甘遂>醋大戟>醋芫花,且海藻占八成以上,甘遂、大戟和芫花均用其醋炙品。就配比而言,除了海藻用量常超过炙甘草(常为炙甘草的2~3倍)外,醋甘遂、醋芫花和醋大戟的用量均常低于炙甘草,且均常为炙甘草用量的1/10最多见。就与甘草组十八反药组配伍的药物情况而言,与炙甘草反药组配伍前6名的药物分别为茯苓、桂枝、白芍、牡丹皮、炒桃仁和红参。结论:在十八反甘草组中,与甘草配伍应用最多的为海藻,而甘遂、大戟等的配伍在临床上均有应用,说明了十八反同方应用在临床中也是客观存在的,并非绝对的配伍禁忌。本研究将对甘草组十八反药组临床应用组方具有一定的指导意义。
Objective: To investigate the clinical application of eighteen anti-licorice herbs. Methods: To retrieve the application situation of the 18th group of anti-licorice in the top three hospitals in a province for the past 3 years (2009.11-2012.11), and to analyze, summarize and summarize. Results: The frequency of clinical use with licorice root followed by seaweed> vinegar, kufuji> vinegar Euphorbia> vinegar Daphne genkwa, and accounted for more than 80% of seaweed, Kansui, Euphorbia and Daphne genkwa were used vinegar. In terms of ratio, in addition to the amount of seaweed often exceed the Zhigancao (often Baked Licorice 2 to 3 times), the vinegar kusnezoffi, vinegar and Eugenia Euphorbia dosage is often lower than the Zhigancao, and are often Baked Licorice dosage 1/10 most see. For licorice group 18 anti-drug group compatibility of drugs, with the Zhigancao anti-drug group compatibility of the top 6 drugs were Poria, Guizhi, white peony, moutan, fried peach and red ginseng. Conclusion: In the eighteen anti-licorice group, compatibility with licorice is the most widely used seaweed, while the compatibility of kunsui, euphorbia and so on are clinically applied, indicating that eighteen anti-same side application is also objective in clinical practice, Not absolutely incompatible taboos. This study will be of licorice group of 18 anti-drug group clinical application of prescription has some significance.