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目的 探讨非内膜样子宫内膜癌的更合适治疗方式。方法 收集 2 0年来经我院治疗的非内膜样子宫内膜癌 138例 ,比较 5种病理亚型的肌层浸润、累及宫颈、子宫外扩散、脉管浸润及 1年、3年、5年存活率情况。结果 19例粘液腺癌及 5 6例角化腺癌的 5年存活率均达到 10 0 % ,说明该两种病理类型具有较低的恶性生物学行为 ;而 38例鳞腺癌、2 0例透亮细胞癌、4例浆液乳头状腺癌的 5年存活率依次为 76 31%、72 2 2 %及 40 0 0 % ,可能与该三类肿瘤较易发生深肌层浸润、子宫外扩散及脉管浸润有关。结论 非内膜样子宫内膜癌病例应根据不同病理亚型采取不同的手术范围及术后辅助治疗
Objective To investigate the more suitable treatment of non-endometrial endometrial cancer. Methods Totally 138 cases of non-endometrioid endometrial carcinoma treated by our hospital in 20 years were collected. Myometrial invasion of 5 pathological subtypes was compared with that of cervical, extrauterine proliferation, vascular invasion and 1, 3, 5 Annual survival rate. Results The 5-year survival rates of 19 cases of mucinous adenocarcinoma and 56 cases of keratinized adenocarcinoma all reached 100%, indicating that these two pathological types had low malignant biological behavior. In 38 cases of squamous cell carcinoma, 20 cases Translucent cell carcinoma, 4 cases of serous papillary adenocarcinoma of the 5-year survival rates were 76 31%, 72 2 2% and 40 0 0%, and these three tumors may be more prone to deep myometrial invasion, extrauterine proliferation and Invasion of vascular involvement. Conclusion Non-endometrial-like endometrial cancer cases should be based on different pathological subtypes to take a different scope of surgery and postoperative adjuvant therapy