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海南省 1994～ 1999年共报告 173例急性弛缓性麻痹 (AFP)病例 ,其中 47例分离出非脊髓灰质炎 (脊灰 )肠道病毒 (NPEV) ,NPEV分离阳性率为 2 7 17%。经鉴定 ,所有分离出的NPEV可分为柯萨奇病毒 (Coxsackie ,Cox .)A9( 1例 )、Cox .B2 ( 2例 )、B3 ( 1例 )、B6( 2例 ) ,埃柯病毒 (Entericcytopathichumanorphanvirus,ECHO) 11个型 ( 3 1例 ) ,肠道病毒 (EV) 70、71型 (各 1例 ) ,“腺病毒 ?”( 3例 ) ,尚有 5例无法分型。其中男性病例占 68 0 9% ,发病以小年龄组为主 ,3岁以下的病例占 87.2 3 % ,95 .74%的患者口服脊灰疫苗 (OPV)免疫史≥ 3次。海南省NPEV感染引起的AFP病例的肢体麻痹 68.0 9% ( 3 2 / 47)为单瘫 ;47例AFP病例中有 2例于发病 60天后仍残留麻痹 ,分别为ECHO7和EV71型感染病例。NPEV感染是AFP病例的重要病因之一 ,应当引起临床医生、防疫工作者和儿童家长的高度重视 ,做到早诊断、早治疗、早康复。
A total of 173 cases of acute flaccid paralysis (AFP) were reported from 1994 to 1999 in Hainan Province. Of them, 47 cases were isolated from non-poliomyelitis (polio) enterovirus (NPEV). The positive rate of NPEV was 27.17%. All isolated NPEVs were identified as Coxsackie Cox. A9 (1 case), Cox. B2 (case 2), B3 (case B6), Echovirus There were 11 cases of Entericcytopathichumanorphanvirus (ECHO), 70 cases of Enterovirus 71 (1 case) and 3 cases of Enterovirus (3 cases). Among them, 68 0 9% were male cases, the incidence was mainly in the younger age group, 87.2% were under 3 years of age, and 95.74% of the patients had ≥3 oral poliomyelitis (OPV) immunization history. Paralysis of limbs in AFP cases caused by NPEV infection in Hainan Province was 68.0 9% (3/2/47), and paralysis was observed in 2 of 47 cases of AFP cases after 60 days of onset, which were respectively ECHO7 and EV71 infection cases. NPEV infection is one of the important causes of AFP cases, clinicians, epidemic prevention workers and parents of children should be given great attention to early diagnosis, early treatment and early recovery.