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目的 :探讨蛋白 C含量在急性脑血管病中变化及意义。方法 :用 ELISA法检测 35例脑梗死者、2 5例脑出血者和 2 5例对照者血浆蛋白 C含量。结果 :急性脑梗死患者血浆蛋白 C含量 (PC:Ag)明显降低 ,较对照组有显著差异 (P<0 .0 1 )。急性脑出血患者 PC:Ag无明显变化 ,较对照组无显著差异 (P>0 .0 5)。结论 :蛋白 C是体内重要抗凝因子 ,它的缺乏与血栓形成有关 ,急性脑梗死患者蛋白 C因参与抗凝过程被消耗而降低。脑出血患者未涉及体内蛋白 C合成和活化无显著变化
Objective: To investigate the changes and significance of protein C in acute cerebrovascular disease. Methods: Plasma protein C levels in 35 cerebral infarction patients, 25 cerebral hemorrhage patients and 25 healthy controls were detected by ELISA. Results: The plasma protein C (PC: Ag) in patients with acute cerebral infarction was significantly lower than that in the control group (P <0.01). PC: Ag in patients with acute cerebral hemorrhage did not change significantly compared with the control group (P> 0.05). CONCLUSION: Protein C is an important anticoagulant factor in the body and its deficiency is related to thrombosis. Protein C in patients with acute cerebral infarction is reduced due to its involvement in anticoagulation. Intracerebral hemorrhage patients did not involve the synthesis and activation of protein C no significant change