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目的探讨心率变异性(HRV)时域分析对2型糖尿病(DM)并发心脏事件的危险性预测价值。方法将2000年3月至2003年9月公安卫生学校附属医院内科住院的56例2型 DM 患者分为单纯组和心脏事件组,分别比较两组24h HRV 时域分析指标和56例2型 DM 患者与38名正常人的24 h HRV 时域分析指标。所有对象平均随访24个月。结果 2型糖尿病患者 HRV 时域分析指标较正常对照组明显减低,P<0.01;观察组的HRV 时域分析指标均较对照组明显减低,P<0.01;且事件组的 HRV 时域分析指标亦较单纯组明显减低,P<0.01。结论 HRV 时域分析指标降低,2型 DM 患者发生心脏事件的危险性增大,HRV 时域分析是预测2型 DM并发心脏事件的有效方法。
Objective To investigate the predictive value of heart rate variability (HRV) temporal analysis in the risk of type 2 diabetes mellitus (DM) complicated with cardiac events. Methods 56 type 2 DM patients hospitalized in the Affiliated Hospital of Public Security School from March 2000 to September 2003 were divided into simple group and cardiac event group. The 24h HRV time-domain analysis indexes and 56 cases of type 2 DM 24 h HRV time domain analysis of patients and 38 normal subjects. All subjects were followed up for an average of 24 months. Results The index of HRV in patients with type 2 diabetes mellitus was significantly lower than that of the control group (P <0.01). The index of HRV time domain analysis in the observation group was significantly lower than that in the control group (P <0.01), and HRV time domain analysis index Compared with the simple group was significantly reduced, P <0.01. Conclusions The index of time-domain analysis of HRV is decreased, and the risk of cardiac events is increased in patients with type 2 DM. Time-domain analysis of HRV is an effective method for predicting type 2 DM complicated with cardiac events.