疟疾是世界上最严重的寄生虫病之一 ,全球每年发病人数达 3～ 5亿 ,其中 10 0～ 2 0 0万人死于此病。疟疾的感染和发病主要发生在发展中国家 ,特别是儿童 ,同时也给进入疫区的商人、游客和军队的部署构成严重的威协。随着疟原虫对抗疟药物的耐药性以及按蚊对杀虫剂耐药性的增加 Malaria is one of the most serious parasitic diseases in the world with an annual incidence of 350 million to 500 million people worldwide, of which 10 to 20 million die from the disease. Infection and incidence of malaria occur mainly in developing countries, especially children, and also constitute a serious threat to the deployment of traders, tourists and troops entering the affected areas. As Plasmodium resistance to antimalarial drugs and anopheline resistance to insecticides increase