目的调查分析深圳市龙岗区2012-2013年吸毒人群的艾滋病病毒(HIV)、丙型肝炎病毒(HCV)以及梅毒螺旋体(TP)的感染状况,为吸毒人群的防治和干预提供科学依据。方法采用问卷调查方法了解2012-2013年深圳市龙岗区吸毒人群的健康状况并对该人群进行HCV、HIV、TP等血清学检测,对检测结果进行统计分析。结果 801名吸毒人员共检出HCV、HIV、TP抗体阳性227、15、65例。其中男性HCV感染率(29.58%)明显高于女性(17.28%),差异有统计学意义(χ2=16.3,P<0.01);男女HIV的感染率分别为1.87%、2.47%,差异无统计学意义;男性TP感染率为7.50%,低于女性的13.58%(χ2=7.90,P<0.01)。HCV抗体感染率41~岁最高(50.00%),其次是31~岁(37.80%);HIV抗体感染以21~(2.67%)和31~岁(1.22%)年龄组为主;TP抗体感染以31~(15.04%)和41~(18.75%)年龄组为主。重叠感染情况:HCV和TP、HCV和HIV、HIV和TP的重叠感染率分别为3.37%、0.62%、0.12%,HCV、HIV和TP混合感染率为0。结论近年深圳市龙岗区吸毒人群HIV、HCV和TP的感染率处在较高水平,应加强宣传健康教育和进行有效防治干预,降低吸毒人群传染病的感染率。 Objective To investigate and analyze the infection status of HIV, HCV and TP from 2012 to 2013 in Longgang District, Shenzhen to provide a scientific basis for the prevention and intervention of drug addicts. Methods A questionnaire survey was conducted to investigate the health status of drug addicts in Longgang District of Shenzhen City from 2012 to 2013 and the serological tests of HCV, HIV and TP were conducted in this population, and the results were statistically analyzed. Results A total of 801 drug addicts were detected positive for HCV, HIV, TP antibody 227,15,65 cases. The infection rate of HIV among men and women was 1.87% and 2.47%, respectively, with no statistical difference (χ2 = 16.3, P <0.01). The prevalence of HCV among men was significantly higher than that of women (29.58% vs 17.28% Significance; male TP infection rate was 7.50%, lower than 13.58% of women (χ2 = 7.90, P <0.01). The prevalence of HCV antibody was the highest in 41 years (50.00%), followed by that in 31 years (37.80%). The prevalence of HIV antibody was 21.2% (2.67%) and 31- (1.22%) in age group. 31 ~ (15.04%) and 41 ~ (18.75%) age groups. Overlapping infections: The rates of overlapping infections of HCV and TP, HCV and HIV, HIV and TP were 3.37%, 0.62% and 0.12%, respectively, and the combined infection rates of HCV, HIV and TP were zero. Conclusion In recent years, HIV, HCV and TP infection rates among drug users in Longgang District of Shenzhen City are at a high level. Health education should be strengthened and effective prevention and intervention should be strengthened to reduce the infection rate of infectious diseases among drug users.