引言妊娠急性脂肪肝(acute fatty liver of pregnancy,AFLP)是妊娠晚期发生的一种少见的致命性疾病,发病机制不明。目前认为此病与胎儿脂肪酸运转以及线粒体氧化障碍有关。为了解AFLP发病是否也有体液免疫反应参与。我们对1997年以来我院确诊为AFLP的3例肝穿标本,采用免疫组化染色方法,观察肝组织中各种免疫球蛋白和补体的沉积情况。 Introduction Acute fatty liver of pregnancy (AFLP) is a rare and fatal disease that occurs in the third trimester of pregnancy. The pathogenesis is unknown. The disease is currently thought to be associated with fetal fatty acid functioning and mitochondrial oxidative disorders. To understand whether the incidence of AFLP humoral immune response is also involved. We since 1997, our hospital diagnosed with AFLP in 3 cases of liver specimens, immunohistochemical staining method to observe the liver tissue of various immunoglobulins and complement deposition.