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目的总结分析中药制剂致过敏性休克的特点及规律,为临床合理用药提供依据。方法检索《中国期刊全文数据库》1999年1月—2008年5月中药制剂致过敏性休克的文献报道,进行统计、分析。结果涉及31种药物,4种剂型,主要为静脉给药,计68例,占86.08%。过敏性休克大多发生在30min内(60例,占77.22%)。结论临床医师、药师应重视中药制剂不良反应,合理用药,加强监护,确保用药安全、有效。
Objective To summarize and analyze the characteristics and rules of anaphylactic shock caused by traditional Chinese medicine preparations and provide the basis for clinical rational drug use. Methods The Chinese Journal Full-text Database was searched from January 1999 to May 2008, and the literature reports about the allergic shock caused by traditional Chinese medicine were collected and statistically analyzed. Results involving 31 kinds of drugs, 4 kinds of dosage forms, mainly for intravenous administration, accounting for 68 cases, accounting for 86.08%. Anaphylactic shock occurred mostly in 30min (60 cases, accounting for 77.22%). Conclusion Clinicians and pharmacists should pay attention to adverse reactions of traditional Chinese medicine preparations, rational use of drugs, strengthen supervision, and ensure that drugs are safe and effective.