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采用吲哚美辛致急性胃溃疡模型，观察并比较了灯盏花素与西米替丁对胃溃疡的保护作用。结果表明：灯盏花素可使吲哚美辛所致的胃溃疡（出血点）面积明显减少（与生理盐水对比，P＜0．05），溃疡抑制率达70.7％，西米替丁的溃疡抑制率为85．3％，二者相比差异无显著（P＞0．05）。
Indomethacin induced acute gastric ulcer model was used to observe and compare the protective effects of breviscapine and cimetidine on gastric ulcer. The results showed that: Breviscapine can significantly reduce the area of gastric ulcer caused by indomethacin (compared with saline, P <0.05), the inhibition rate of ulcer was 70.7%, the ulcer of cimetidine The inhibition rate was 85.3%, there was no significant difference between them (P> 0.05).