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本文报告7例伴多灶性上皮样组织细胞反应的非何杰金氏淋巴瘤(Lennert淋巴瘤)其共同的光镜形态学特点为,显然良性的上皮样组织细胞形成均匀分布的簇,与各种异型淋巴细胞充分混合,形成弥漫性结构,淋巴结的结构被破坏。该瘤罕见。国内患者的年龄和性别分布与国外报告者相似。多见于老年人,男略多于女。临床上皆有淋巴结肿大,且半数病例为全身性淋巴结肿大。治疗效果差,病程短,预后不佳。结合文献,对该瘤的诊断和鉴别诊断要点、性质和组织发生进行讨论。作者认为,其属于非何杰金氏恶性淋巴瘤的一型。
In this paper, we report 7 common morphologic features of non-Hodgkin’s lymphoma (Lennert’s lymphoma) with multifocal epithelial cell-like response to epithelial cells. It is clear that benign epithelial-like tissue cells form uniformly distributed clusters with A variety of atypical lymphocytes mixed to form a diffuse structure, the structure of lymph nodes is destroyed. The tumor is rare. The age and gender distribution of domestic patients is similar to that of foreign speakers. More common in the elderly, slightly more men than women. Lymph nodes are clinically all, and half of the cases of systemic lymphadenopathy. Poor treatment, short course, poor prognosis. Combined with the literature, the diagnosis and differential diagnosis of the tumor points, nature and organization were discussed. The authors believe that it belongs to a type of non-Hodgkin’s lymphoma.