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目的探讨胰岛素样生长因子-1(IGF-1)、超氧化物歧化酶(SOD)、同型半胱氨酸(Hcy)、胰岛素样生长因子结合蛋白3(IGFBP-3)、生长激素(h GH)、促红细胞生成素(EPO)、白介素6(IL-6)、总胆固醇(CHO)、甘油三酯(TG)、高密度脂蛋白(HDL-C)、低密度脂蛋白(LDL-C)、载脂蛋白AI(Apo AI)、载脂蛋白B(Apo B)、尿素(UREA)、肌酐(CREA)、胱抑素C(Cys-C)、皮质醇(COR)及促肾上腺皮质激素(ACTH)在冠心病患者检测中的价值。方法选取60例冠心病患者作为冠心病组,选取60例健康体检者作为正常对照组,分别对各血液指标进行检测。结果冠心病组血清Hcy、COR、EPO水平均高于正常对照组,差异有统计学意义(P<0.05),冠心病组血清SOD、IGF-1水平均低于正常对照组,差异有统计学意义(P<0.05)。冠心病组血清HDL-C、LDL-C、Apo AI、Apo B、Cys-C水平与正常对照组比较,差异有统计学意义(P<0.05)。结论冠心病患者检测IGF-1、SOD、Hcy、EPO、COR、HDL-C、LDL-C、Apo AI、Apo B和Cys-C水平,对临床有重要指导意义。
Objective To investigate the effects of insulin-like growth factor-1 (IGF-1), superoxide dismutase (SOD), homocysteine (Hcy), insulin-like growth factor binding protein 3 (IGFBP- (EPO), interleukin 6 (IL-6), total cholesterol (CHO), triglyceride (TG), high density lipoprotein (HDL-C), low density lipoprotein (LDL- , Apo AI, Apo B, UREA, CREA, Cys-C, COR and ACTH ACTH) in the detection of coronary heart disease patients. Methods Sixty patients with coronary heart disease were selected as coronary heart disease group. Sixty healthy subjects were selected as the normal control group, and the blood parameters were measured respectively. Results The levels of serum Hcy, COR and EPO in CHD group were significantly higher than those in control group (P <0.05). The levels of serum SOD and IGF-1 in CHD group were lower than those in control group Significance (P <0.05). The levels of HDL-C, LDL-C, Apo AI, Apo B and Cys-C in CHD group were significantly different from those in control group (P <0.05). Conclusion The detection of IGF-1, SOD, Hcy, EPO, COR, HDL-C, LDL-C, Apo AI, Apo B and Cys-C in patients with coronary heart disease is of clinical significance.