伤寒肠热病(伤寒和副伤寒)是严重的系统性疾病,具有持续发热和胃肠综合征特性。通常由伤寒沙门氏菌和甲型、乙型、丙型副伤寒沙门氏菌引起。1986年,世界范围的伤寒病人估计有3千3百万人。此病在许多发展中国家流行,旅行者存在相当的患病风险。 用适当的抗生素治疗伤寒肠热病是必要的,因为此疾病的特性,它应该一出现就进行临床诊断。目前氯霉素、氨苄青霉素和增效磺胺甲基异噁唑是治疗伤寒肠热病的首进抗生素,但对氯霉素、氨苄青霉素和增效磺胺甲基异噁唑耐药性的 Typhoid enteric fever (typhoid and paratyphoid) is a serious systemic disease with persistent fever and gastrointestinal syndrome characteristics. Often caused by Salmonella typhi and A, B, Salmonella paratyphi Salmonella. In 1986, an estimated 33 million typhoid patients worldwide. The disease is prevalent in many developing countries and travelers have a considerable risk of getting sick. Proper antibiotic treatment of typhoid fever is necessary because of the nature of the disease and it should be clinically diagnosed as soon as it emerges. Currently, chloramphenicol, ampicillin and synergistic sulfamethoxazole are the first antibiotics to treat typhoid enteric fever, but resistant to chloramphenicol, ampicillin and synergistic sulfamethoxazole