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目的:观察清热化湿法联合利巴韦林治疗小儿手足口病(普通型)疗效。方法:将符合诊断标准的76例患者随机分为两组,对照组38例,口服利巴韦林颗粒;治疗组38例,在对照组基础上口服中药汤剂,以清热化湿治疗。疗程均为7d,观察治疗前后两组临床症状、体征的变化。结果:治疗组总有效率94.74%,对照组总有效率84.21%,治疗组疗效优于对照组(P<0.05);临床症状治疗组改善情况显著优于对照组(P<0.01),两组无严重不良反应发生。结论:清热化湿法联合利巴韦林治疗小儿手足口病优于单纯利巴韦林治疗。
Objective: To observe the curative effect of clearing heat and dampness combined with ribavirin in the treatment of hand-foot-mouth disease in children. Methods: 76 patients with diagnostic criteria were randomly divided into two groups, the control group of 38 patients, oral ribavirin particles; the treatment group of 38 patients on the basis of the control group oral Chinese medicine decoction to heat dampness treatment. The duration of treatment was 7 days. The changes of clinical symptoms and signs before and after treatment were observed. Results: The total effective rate was 94.74% in the treatment group and 84.21% in the control group, and the curative effect in the treatment group was better than that in the control group (P <0.05). The clinical symptom improvement group was significantly better than the control group (P <0.01) No serious adverse reactions occurred. Conclusion: Qingre Huazhuo combined with ribavirin treatment of children with hand-foot-mouth disease is superior to the treatment of ribavirin alone.