十五内酯是一种具有珍贵的麝香香气的大环麝香类化合物 ,是配制名贵香水的重要香料。由于十五内酯在氢焰离子化检测器中有强烈的信号响应 ,故十五内酯的含量可用气相色谱法进行测定。采用十六酸甲酯作为内标物 ,用气相色谱法的内标法进行定量测定十五内酯 ,方法简单、快速 ,测定结果准确、可靠 Pentadecalactone is a macrocyclic musk that has a precious musk aroma and is an important fragrance for the preparation of luxury perfumes. Since fifteen lactones in the hydrogen flame ionization detector has a strong signal response, so fifteen lactone content can be determined by gas chromatography. Methyl palmitate was used as internal standard, and the internal standard method of gas chromatography was used for the quantitative determination of pentadecalactone. The method was simple and rapid, the results were accurate and reliable