Purpose:To evaluate the efficacy and safety of using coreoplasty,and an iris-supported Artisan intraocular lens (IOL),for mydriasis and aphakic correction in post-traumatic vitrectomized eyes.Methods:A total of 17 aphakic patients were admitted between April 2009 and April 2010 to the ophthalmologic department of Xiamen Eye Centre.All eyes had previously received lens removal and vitrectomy.After the retina stabilized and corrected visual acuity improved,the iris was sutured.The Artisan IOL was fixated onto the iris surface.Patients were followed-up at one day,one week,one month and three months postoperatively.The following outcomes were assessed:symptoms of photophobia and glare,uncorrected visual acuity (UCVA),best-corrected visual acuity (BCVA),intraocular pressure (IOP),endothelial cell density (ECD).The diameter of pupil and the anterior chamber depth (ACD)were measured by the anterior segment optical coherence tomography (OCT).Results:Artisan IOLs were successfully implanted in all aphakic eyes.Postoperatively,improvement was observed in photophobia and glare symptoms.UCVA was enhanced in all patients (six eyes had better UCVA postoperatively than BCVA preoperatively).However,there were no significant changes in IOP.Mean loss of ECD was 336.06/mm2.Mean postoperative pupil diameter was 3.67±0.41 mm,compared with 5.67±0.57 mm preoperatively(P＜0.05).Mean ACD was reduced by 0.88 mm (3.38±0.33 mm preoperatively vs 2.50±0.35 mm postoperatively,P＜0.05).Conclusion:Surgery that combined coreoplasty and Artisan IOL implantation was a safe and effective treatment for correcting aphakia and mydriasis in post-traumatic vitrectomized eyes.