c- fos作为即刻早期基因的一种 ,编码的 Fos蛋白组成了其他许多基因的转录调控因子 ,因而可将外界信号级联放大 ,造成细胞长期的生理功能改变。近年来 ,对 c- fos进行了广泛而深入的研究 ,并取得了一定的成果。本文就其结构、功能及其与癫的关系作一综述。 As a kind of immediate early gene, c-fos encodes the transcriptional regulator of many other genes, which can amplify the external signal cascade and cause long-term physiological changes in cells. In recent years, c-fos has been extensive and in-depth study, and achieved some results. This article reviews its structure, function and its relationship with epilepsy.