[Objective] The experiment aimed to explore sedation of dried ginger. [Method] By compared the experimental results before and after intragastric administration, the influences of decoction of dried ginger at different concentrations (1, 2,3 mg/ml) on locomotor activities of white mice. [Result]When the decoction of dried ginger was 1 g/ml, the time of free movements and the number of raising forelimbs of mice were obviously detained (2.5 h after intragastric administration). When the decoction of dried ginger was 2 g/ml, the time of free movements and the number of raising forelimbs of mice were obviously influenced however the inhibition time is short than that of 1 g/ml. When the decoction of dried ginger was 3 g/ml, the inhibition is not obvious. [Conclusion] Dried ginger had some sedation effect which was related to its dosage.