论文部分内容阅读
目的探究不同剂量阿托伐他汀治疗冠心病慢性心力衰竭的疗效及安全性。方法选128例冠心病慢性心力衰竭患者,对患者应用不同治疗方案进行治疗,观察疗效及安全性。结果试验组LVEDD、LVESD、LVEF、血浆BNP等各项心功能参数均显著优于对照组(P<0.05)。试验组甘油三酯、胆固醇等各项血脂参数改善幅度均显著优于对照组(P<0.05)。试验组不良反应发生率显著优于对照组(P<0.05)。结论临床治疗冠心病慢性心力衰竭患者的过程中,高剂量阿托伐他汀治疗可显著改善患者的心功能各项指标,并有助于血脂参数的改善,避免发生不良反应,有利于患者的预后。
Objective To investigate the efficacy and safety of different doses of atorvastatin in patients with chronic heart failure of coronary heart disease. Methods 128 cases of CHD patients with chronic heart failure, the treatment of patients with different treatment options to observe the efficacy and safety. Results The cardiac function parameters of LVEDD, LVESD, LVEF and plasma BNP in the experimental group were significantly better than those in the control group (P <0.05). The experimental group, triglyceride, cholesterol and other lipid parameters were significantly better than the control group (P <0.05). The incidence of adverse reactions in the experimental group was significantly better than that in the control group (P <0.05). Conclusion In the clinical treatment of CHD patients, high-dose atorvastatin treatment can significantly improve the cardiac function in patients with various indicators, and contribute to the improvement of blood lipid parameters, to avoid adverse reactions, is conducive to the prognosis of patients .