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目的:观察皮肌炎(DM)和多发性肌炎(PM)与头颈部恶性肿瘤的关系。方法:收集1994~2003年北京协和医院诊治的136例DM和PM患者的临床资料,分析其中6例并发头颈部恶性肿瘤患者的临床特点。结果:136例患者中,并发恶性肿瘤17例,其中头颈部恶性肿瘤6例:鼻咽癌4例,非霍奇金淋巴瘤1例,下咽癌1例,占恶性肿瘤的35.29%(6/17)。结论:鼻咽癌是DM和PM患者最易并发的头颈部恶性肿瘤;对于DM和PM患者,应该将鼻咽喉内镜检查列为常规,以期对潜在的头颈部恶性肿瘤做出早期诊断和治疗。
Objective: To observe the relationship between dermatomyositis (DM) and polymyositis (PM) and head and neck cancer. Methods: The clinical data of 136 DM and PM patients diagnosed and treated in Peking Union Medical College Hospital from 1994 to 2003 were collected, and the clinical features of 6 patients with head and neck malignant tumor were analyzed. Results: Of the 136 patients, 17 were malignant tumors, of which 6 were head and neck malignancies: 4 were nasopharyngeal carcinoma, 1 non-Hodgkin’s lymphoma, 1 hypopharyngeal carcinoma, accounting for 35.29% of all malignant tumors 6/17). CONCLUSIONS: Nasopharyngeal carcinoma is the most common malignant head and neck cancer in patients with DM and PM. Nasopharyngeal endoscopy should be routinely performed in patients with DM and PM to make early diagnosis of potential head and neck malignancies And treatment.