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乙型肝炎病毒(HBV)基因组是一个环状的、长约32000bp的DNA分子。与其它能独立复制的双链DNA病毒相比,HBV是迄今已知能对人感染的病毒中最小的基因组。因而,HBV利用其遗传物质节俭是不奇怪的。它通过两种罕见的排列来达到这一点,即:蛋白质由重迭的翻译框架编码;所有调节信号都存在于蛋白质编码的序列中。因此,HBV从它的基因组的许多区域获得重复利用的能力。从进化观点看,这显示了该病毒结构的精巧。
The Hepatitis B virus (HBV) genome is a circular, approximately 32,000 bp DNA molecule. Compared to other double-stranded DNA viruses that replicate independently, HBV is the smallest of the viruses known to date to infect humans. Thus, it is not surprising that HBV uses its genetic material to thrifty. It does this by two rare permutations: the proteins are encoded by overlapping translation frames; all of the regulatory signals are present in the protein-encoded sequence. Therefore, HBV gains the ability to recycle from many areas of its genome. From an evolutionary point of view, this shows the delicate structure of the virus.