肥厚型心肌病(HCM)是最常见的心肌病,发病率约1∶500,约60%的患者有可询及的家族史,呈常染色体显性遗传[1]。HCM是原发于心肌的遗传性疾病,心室肥厚是其诊断依据,需排除高血压等疾病和运动员心脏肥厚。HCM临床表现多样:可无症状,可轻度胸闷、心悸、呼吸困难,亦可出现恶性室 Hypertrophic cardiomyopathy (HCM) is the most common cardiomyopathy, with a prevalence of about 1: 500. About 60% of patients have a familial history of autism and autosomal dominant inheritance [1]. HCM is a primary genetic disease in the myocardium, ventricular hypertrophy is the basis for its diagnosis, need to rule out hypertension and other diseases and athletes with cardiac hypertrophy. HCM various clinical manifestations: asymptomatic, mild chest tightness, palpitations, difficulty breathing, malignant may also occur