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目的了解老年COPD患者合并肺部真菌感染的病因和预后,指导临床合理用药。方法回顾性分析老年慢性阻塞性肺病(COPD)60例,其中合并肺部真菌感染的30例,无肺部真菌感染的病例30例,分析统计两组抗生素使用情况。结果老年COPD合并肺部真菌感染,抗生素使用种类明显较非真菌感染组多,且使用时间较非真菌感染组长,比较差异均有统计学意义(P<0.05)。结论对于老年COPD合并肺部感染患者治疗,一种抗生素可控制的感染,应避免多种药物联用,减少广谱抗生素的应用,根据药物敏感试验选用抗生素,缩短疗程。
Objective To understand the etiology and prognosis of pulmonary fungal infection in elderly patients with COPD and to guide the rational use of clinical medicine. Methods A retrospective analysis of 60 elderly patients with chronic obstructive pulmonary disease (COPD), including 30 cases of pulmonary fungal infection, no cases of pulmonary fungal infection in 30 cases, analysis of the use of antibiotics in both groups. Results Compared with the non-fungal infection group, COPD patients with pulmonary fungal infection in the elderly group had significantly more antibiotic use than the non-fungal infection group, and the difference was statistically significant (P <0.05). Conclusions For the treatment of elderly patients with COPD complicated with pulmonary infection, an antibiotic-controlled infection should avoid the combination of multiple drugs and reduce the use of broad-spectrum antibiotics. Antibiotics are selected according to drug susceptibility tests to shorten the course of treatment.