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开展学术争鸣,有利于科学进步值得提倡。两文的焦点在于膦甲酸的副作用,其静脉给药时全身副作用较多,最常见的毒副作用是肾功能受损、电解质失衡(尤其是低磷酸盐血症)和贫血,有少数患者由于毒副作用大而需终止用药。外用时的副作用为局部皮肤刺激。故此药仅限于耐药而导致更安全的阿昔洛韦治疗失败的患者(见《性病诊疗与预防》叶顺章,邵长庚主编.人民卫生出版社,2002:279)。前文的参考文献[3]不易找到,也可换为:美国CDC性传播疾病治疗指南(卫生部疾病控制司等.性病情况简报2002;16(6):15).
Academic debate is conducive to scientific progress is worth promoting. The focus of both papers is on the side effects of foscarnet, which have more systemic side effects when administered intravenously, the most common side effects being impaired renal function, electrolyte imbalance (especially hypophosphatemia), and anemia. Side effects and need to terminate the medication. Side effects when topical skin irritation. Therefore, the drug is limited to patients resistant to acyclovir safer treatment (see “STD disease treatment and prevention,” Ye Shunzhang, Shao Changgeng editor. People’s Health Publishing House, 2002: 279). The previous references [3] are not easy to find and can be read as: Guidelines for the Treatment of Sexually Transmitted Disease in the United States of America (Department of Disease Control, Ministry of Health, etc. STD Fact Sheet 2002; 16 (6): 15).