多数白血病病人发病是急骤的,但也有少数病人在发展成急性白血病以前有一个相当长的非白血病性的血液异常过程。白血病前期血细胞量的变化已有不少报告,如贫血、白细胞减少和血小板减少伴有骨髓增生过盛等等。但关于血细胞质的异常却很少报告。作者报告广岛大学医院6例病人,年龄为20～61岁,其 Most leukemia patients with the onset of a sudden, but there are a small number of patients in the development of acute leukemia before there is a fairly long non-leukemia hematological abnormalities. Pre-leukemia cells have been many changes in blood cell volume, such as anemia, leukopenia and thrombocytopenia with hypermyosis and so on. However, abnormalities on the cytoplasm of the blood are rarely reported. The authors report 6 cases of Hiroshima University Hospital, aged 20 to 61 years old