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目的:观察氯沙坦单用和与氨氯地平合用治疗高血压合并高尿酸血症的疗效。方法:31例患者随机分为观察组和对照组,对照组单用氯沙坦;观察组联合用药,观察用药前后两组患者血压、血尿酸的变化情况。结果:联合用药组血压控制有效率明显高于对照组(P<0.05);联合用药组排尿酸作用优于对照组(P<0.05)。结论:氯沙坦与氨氯地平联合用药能达到降压、排尿酸的双重功效,耐受性好,疗效确切。
Objective: To observe the efficacy of losartan alone and amlodipine in the treatment of hypertension combined with hyperuricemia. Methods: Thirty-one patients were randomly divided into observation group and control group. The control group was treated with losartan alone. The observation group was given combination therapy to observe the changes of blood pressure and serum uric acid before and after treatment. Results: The effective rate of blood pressure control in combination group was significantly higher than that in control group (P <0.05). Administration of uric acid in combination group was better than that in control group (P <0.05). Conclusion: The combination of losartan and amlodipine can achieve the dual effect of blood pressure lowering and uricosuric acid with good tolerability and exact curative effect.