李时珍写成的医药学巨著《本草纲目》,载药1892味,内有有毒中药239味,其分类、应用及解毒方法等均较明以前诸本草详细,对后世研究有毒中药有一定贡献。本文仅从以下几方面进行阐述:一、创毒草药分类;二、用毒药治厥证;三、重视毒药炮制;四、强调毒药配伍;五、掌握剂量用法;六、详记解毒方法;七、敢批前人谬误;八、补充实践经验。 Li Shizhen’s medical masterpiece “Compendium of Materia Medica” contained 1892 tastes, containing 239 tastes of toxic traditional Chinese medicines. Its classification, application and detoxification methods were all more detailed than those of the Ming Dynasty. They have contributed to the study of toxic traditional Chinese medicine in later generations. This article is only elaborated from the following aspects: First, the classification of virus-producing herbs; Second, the use of poisons to cure sputum syndrome; Third, pay attention to poison processing; Fourth, emphasize the compatibility of poisons; Fifth, master the dose usage; Six, detailed detoxification method; Seven , Dare to criticize the predecessors; VIII, to add practical experience.