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目的了解靖江地区不同人群骨质疏松症(OP)状况和变化规律,探讨血清生化指标检测在骨质疏松症中诊断的应用。方法采用超声骨密度仪对2010-2012年靖江地区1 565名不同人群进行骨密度检测,并对其血清中骨钙素(BGP)、碱性磷酸酶(ALP)、钙离子等生化指标进行检测,按照年龄和群体进行分析。结果靖江地区骨质疏松发生率随年龄增长而增高,血清BGP水平随年龄增长而降低,血清ALP水平在60岁以上人群中明显升高。钙离子在各类群体和年龄中没有明显变化。30岁以上人群OP发病率增加,60岁以上老年人OP发生率为33.3%。结论靖江地区不同年龄和不同人群骨密度变化规律不同,老年人、机关工作人员和离退休人员骨量流失严重,是OP的高危人群和防治对象;OP发病率随年龄增长而增高,监测血清BGP和ALP水平对OP有辅助诊断价值。
Objective To investigate the status and changes of osteoporosis (OP) in different populations in Jingjiang area and to explore the application of serum biochemical markers in the diagnosis of osteoporosis. Methods The bone mineral density (BMD) of 1 565 different people in Jingjiang from 2010 to 2012 was measured by using ultrasonic bone densitometry. The serum biochemical indexes such as BGP, ALP and calcium were detected , By age and group analysis. Results The incidence of osteoporosis in Jingjiang area increased with age. Serum BGP level decreased with age, serum ALP level was significantly higher in people over 60 years old. Calcium ions in all groups and age did not change significantly. The incidence of OP increased in people over the age of 30, and the incidence of OP in the elderly over the age of 60 was 33.3%. Conclusion The BMD of different age groups and different groups in Jingjiang area varies regularly. The bone loss of elderly, institutional workers and retired staff is serious, which is a high risk group and control object of OP. The incidence of OP increased with age, serum BGP And ALP levels have a diagnostic value for OP.