检测迟发型超敏感(DTH)反应是判断T细胞功能正常与否的一个重要指标。我们以前的研究已发现艾氏腹水癌(EAC)使胸腺发生进行性萎缩,外周血液和外周免疫器官中的T细胞逐渐减少。因此,T细胞介导的DTH反应可能要受到直接的影响。所以,本试验选用SRBC作为致敏原和攻击原,探讨EAC对宿主DTH反应的影响及其可能的机制。 Detection of delayed-type hypersensitivity (DTH) response is to determine whether T cell function is an important indicator of normal or not. Our previous studies have found that Ehrlich ascites carcinoma (EAC) causes a progressive atrophy of the thymus and a gradual decrease in T cells in peripheral blood and peripheral immune organs. Therefore, T cell-mediated DTH responses may be directly affected. Therefore, this study selected SRBC as the allergen and the original attack, explore the EAC host DTH response and its possible mechanism.