目的：探讨硝苯吡啶治疗急性心梗塞的疗效。方法：随机将228例AMI分为三组，硝苯吡啶组和硝苯吡啶加β受体阻滞剂组及对照组。结果：硝苯吡啶组102例，死亡11例，死亡率10．72％；硝苯吡啶加β受体阻滞剂组39例，死亡5例，死亡率为12．82％；对照组87例，死亡12例，死亡率为13．79％。结论：三组相比硝苯吡啶组死亡率最低，但无统计学意义，P＞0．05，故我们认为硝苯吡啶10mg，每日三次对国人是有益的。 Objective: To investigate the efficacy of nifedipine in the treatment of acute myocardial infarction. Methods: 228 cases of AMI were randomly divided into three groups, nifedipine group and nifedipine plus β-blocker group and control group. Results: In the nifedipine group, 102 patients died of 11 cases with a mortality rate of 10.72%. Nifedipine plus β-blocker group of 39 patients died of 5 cases with a mortality rate of 12.82%. In the control group, 87 patients , 12 died, the mortality rate was 13.79%. CONCLUSION: The mortality of the three groups was the lowest compared with nifedipine, but not statistically significant (P> 0.05). Therefore, we think nifedipine 10mg three times a day is beneficial to Chinese people.