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由上海瑞金医院、深圳华大基因等单位组成的科研团队,通过对57例肾上腺皮质肿瘤患者的肿瘤样本进行基因测序,发现了肾上腺瘤致病基因,为肾上腺皮质肿瘤及库欣综合征的诊断、治疗提供了新思路。研究成果于近日在《科学》杂志网站上在线发表。库欣综合征主要是由于肾上腺皮质肿瘤引发的皮质醇过量分泌导致,包括肾上腺皮质腺瘤、肾上腺癌、肾上腺皮质结样增生及肾上腺皮质嗜酸细胞瘤等。肾上腺皮质肿瘤和库欣综合征是内分泌代谢疾病中非常重要的一
A research team consisting of Shanghai Ruijin Hospital and Shenzhen Huada Gene, etc., has sequenced the tumor samples of 57 patients with adrenocortical tumors and found that adrenal tumor-causing genes are responsible for the diagnosis of adrenocortical tumors and Cushing’s syndrome , Treatment provides a new idea. The research results have been published online on Science website recently. Cushing’s syndrome is mainly due to excessive secretion of cortisol caused by adrenal tumors, including adrenal cortical adenoma, adrenal cancer, adrenal cortical hyperplasia and adrenocortical oncocytoma. Adrenocortical tumors and Cushing’s syndrome are very important in endocrine and metabolic diseases