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作者评价硫糖铝乳剂与雷尼替丁短期治疗消化性溃疡的疗效。经内窥镜证实的消化性溃疡患者,随机接受硫糖铝乳剂(1g,一日4次,饭前1小时和睡时服)或雷尼替丁(150mg,一日2次)治疗,两组病人呈可比性。85例完成了4周治疗。对溃疡未愈合者,继续服用硫糖铝或雷尼替丁,共12周。 85例中,硫糖铝治疗组41例和雷尼替丁治疗组44例。2周后溃疡治愈率均为41%,4周后,溃疡愈合率增加,硫糖铝组为76%,雷尼替丁组为73%。12周后,溃疡愈
The authors evaluate the short-term efficacy of sucralfate and ranitidine in the treatment of peptic ulcer. Patients with peptic ulcer confirmed by endoscopy were randomized to receive either sucralfate (1 g, 4 times a day, 1 hour before meals and during sleep) or ranitidine (150 mg twice daily), and two Group of patients was comparable. 85 cases completed the 4 weeks of treatment. Unhealed ulcers, continue to take sucralfate or ranitidine, a total of 12 weeks. Among 85 cases, 41 cases were treated with sucralfate and 44 cases were treated with ranitidine. After 2 weeks, ulcer healing rates were both 41%. After 4 weeks, ulcer healing rates were increased, with sucralfate 76% and ranitidine 73%. After 12 weeks, the ulcer more