论文部分内容阅读
GLOI即乙二醛酶Ⅰ(Glyoxalase Ⅰ,Ec 4.4.1.5)广泛分布于人的红细胞、精液、肌肉,毛根鞘细胞等二十余种不同组织中。它在红细胞中的活性较高。该酶以还原型谷胱甘肽作辅酶,使甲基乙二醛转变为S-乳酰谷胱甘肽。利用还原型谷胱甘肽可抑制淀粉遇碘液呈蓝色的反应,使酶活性带显现。Kompf等于1975年最先发现它具有遗传多态性,表型有2-2;2-1和1-1型三种,分别受第6号染色体短臂上一对共显性等位基因GLOI~1和GLOI~2控制,因而作为一种检测系统应用于法
GLOI glyoxalase Ⅰ (Glyoxalase Ⅰ, Ec 4.4.1.5) widely distributed in human red blood cells, semen, muscle, hair root sheath cells and so on more than 20 different tissues. It is more active in red blood cells. The enzyme uses reduced glutathione as a coenzyme to convert methylglyoxal to S-lactoyl glutathione. The use of reduced glutathione can inhibit the reaction of starch in iodine blue reaction, the enzyme activity with the show. Kompf was first discovered in 1975, it has a genetic polymorphism, phenotype 2-2; 2-1 and 1-1 three, respectively, by a short arm of chromosome 6 co-dominant allele GLOI ~ 1 and GLOI ~ 2 control, so as a detection system used in law