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目的 :探讨对一期手术切除困难的腹部恶性肿瘤术前行介入治疗的意义。材料和方法 :对 13例腹部恶性肿瘤进行介入治疗 ,肝母细胞瘤 6例 ,神经母细胞瘤 4例 ,肾母细胞瘤 2例 ,肾上腺皮质癌 1例。所有病例先行动脉插管造影 ,确定肿瘤主要供血动脉 ,对肿瘤供血动脉行超选择性插管 ,局部注入化疗药物及栓塞剂。结果 :13例中 7例手术切除了肿瘤 ,1例剖腹探查。余 5例通过介入治疗后 ,肿瘤缩小。 13例病人随访 6～ 13个月 ,生存11例。结论 :介入治疗可保证肿瘤局部高浓度化疗药物灌注 ,减少全身副作用 ;又可阻断肿瘤血供 ,使肿瘤缺血坏死 ,达到治疗目的。同时栓塞后 ,肿瘤包膜增厚 ,有利于手术中完整切除肿瘤
Objective : To explore the significance of preoperative interventional treatment for abdominal malignancies with difficult resection. Materials and Methods: 13 cases of abdominal malignant tumors were treated with interventional therapy, 6 cases of hepatoblastoma, 4 cases of neuroblastoma, 2 cases of nephroblastoma, and 1 case of adrenocortical carcinoma. All cases were preceded by arterial intubation angiography to determine the main blood supply artery of the tumor, superselectively intubate the tumor blood supply artery, and locally inject chemotherapy drugs and embolization agents. Results : Of the 13 cases, 7 were surgically resected and 1 was exploratory. In the remaining 5 cases after interventional therapy, the tumors shrank. Thirteen patients were followed up for 6 to 13 months and 11 patients survived. Conclusion: Interventional treatment can ensure high-concentration chemotherapeutic drug perfusion in the tumor and reduce systemic side effects. It can also block tumor blood supply and make the tumor an ischemic necrosis and achieve therapeutic goals. At the same time after embolization, the tumor capsule is thickened, which is conducive to the complete resection of tumor during operation.