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本文利用未成熟大脑对N-甲基-D-天冬氨酸(N-meth-yl-D-aspartate,NMDA)高度敏感,诱导大鼠乳鼠出现特异的屈曲样痉挛的癫癎发作,建立婴儿痉挛的动物模型,运用免疫组化(IHC)技术及Image J图象分析软件,半定量分析致癎乳鼠大脑额叶皮层组织癫癎发作时脑红蛋白(NGB)的表达规律。1材
In this study, we used the immature brain to be highly sensitive to N-methyl-D-aspartate (NMDA) to induce epileptic seizures in rats with specific flexion-like spasm Infantile spasms were used to semi-quantitatively analyze the expression of NGB during the epileptic seizure in the frontal cortex of the suckling rat brain by immunohistochemistry (IHC) and Image J image analysis software. 1 material