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目的探讨高尿酸血症对老年非胰岛素依赖型糖尿病 (NIDDM)慢性并发症的影响。方法取 42 1例老年 NIDDM患者 ,依据是否伴有高尿酸血症 (HUA)分为两组 ,观察一般情况 ,并测量血糖、血脂、血尿酸。结果老年 NIDDM伴有高尿酸血症组冠心病、高血压、急性脑血管意外的患病率明显高于对照组 (P<0 .0 1)。结论高尿酸血症是老年 NIDDM的一个危险因素 ,且增加了慢性并发症的患病率
Objective To investigate the effect of hyperuricemia on chronic complications of non-insulin dependent diabetes mellitus (NIDDM) in the elderly. Methods A total of 421 elderly patients with NIDDM were divided into two groups according to their hyperuricemia (HUA). The general conditions were observed and blood glucose, blood lipid and serum uric acid were measured. Results The prevalence of coronary heart disease, hypertension and acute cerebrovascular accident in elderly patients with NIDDM complicated with hyperuricemia was significantly higher than that in the control group (P <0.01). Conclusions Hyperuricemia is a risk factor for elderly NIDDM and increases the prevalence of chronic complications