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45例原发性蛛网膜下腔出血患者接受了脑脊液净化治疗,多数做了3~5次,最多者做9次。每次脑脊液出量20~70ml,平均总出量168±62ml。4例急性期复发出血。3个月后33例患者基本康复,无明显神经系统后遗症,11例有神经功能缺陷。1例因暴发性肝炎,消化道大出血死亡。作者结合文献讨论了脑脊液净化治疗蛛网膜下腔出血的机理,指出其可清除积血,降低颅压,预防或减轻血管痉挛与迟发性缺血性神经缺陷,降低病死率与致残率。
45 cases of patients with primary subarachnoid hemorrhage received cerebrospinal fluid purification treatment, most done 3 to 5 times, up to 9 times. Each cerebrospinal fluid output 20 ~ 70ml, the average total output of 168 ± 62ml. 4 cases of acute recurrent bleeding. After 3 months, 33 patients recovered basically, no neurological sequelae and 11 neurological deficits. 1 case of fulminant hepatitis, gastrointestinal bleeding died. The authors discussed the mechanism of cerebrospinal fluid purification in treating subarachnoid hemorrhage combined with the literature, pointing out that it can clear hemorrhage, reduce intracranial pressure, prevent or reduce vasospasm and delayed ischemic neurological defects, and reduce mortality and morbidity.