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目的：分析腹腔镜下子宫肌瘤切除术（Laparoscopic myomectomy，LM）和开腹子宫肌瘤切除术（transabdominal myomectomy，TAM）治疗子宫肌瘤的临床疗效与应用价值。方法收集2007年1月1日～2012年12月31日行腹腔镜下子宫肌瘤切除术70例，与开腹子宫肌瘤切除术20例在手术时间、术中出血量、肛门排气时间和住院时间等方面的数据进行对比、分析。结果腹腔镜组与开腹组在手术时间方面差异无统计学意义（P＞0.05），在术中出血量、术后排气时间与住院时间方面腹腔镜组显著优于开腹组，差异具有统计学意义（P＜0.01）。结论腹腔镜下子宫肌瘤切除术具有创伤小、术中出血少、术后恢复快及住院时间短等优点，在一定范围内优于开腹手术，值得医院推广应用。“,”Objective To compare the clinical efifcacy of myomectomy treated with laparotomy and laparos-copy. Methods We collected 70 cases laparoscopic myomectomy and 20 cases of transabdominal myomectomy from January 2007 to December 2012. And we compared the operative time, blood loss, anal exhaust time and length of hospital stay of them. Results There was no signiifcant difference in operative time between them, but laparoscopic myomectomy performed better in the other three aspect. Conclusion Compared with the laparotomy myomectomy, laparoscopy myomectomy has mini trauma, quicker post operative recovery, and less pain. This method is safe and effective.