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为了解血清抗角蛋白自身抗体(AK auto Ab)消长对皮肤病变的影响,首次建立了血清AK auto Ab不同滴度的动物模型,其操作和检测报告如下。 1 材料和方法 健康成年家兔4只,用饱合硫化钠水溶液将腹部及背部毛脱光,取12片1.0cm×0.5cm大小的腹部皮片。将1-3号家兔的皮片真皮面
In order to understand the effect of serum autoantibody AK auto ablation on skin lesions, an animal model with different titers of serum AK auto Ab was established for the first time, and its operation and detection report was as follows. 1 Materials and Methods Four healthy adult rabbits were used to detumrate the abdomen and back hair with saturated sodium sulfide aqueous solution and 12 pieces of 1.0 cm × 0.5 cm abdominal skin were taken. No. 1-3 rabbit skin leather surface