从传统用作驱虫和导泻之用的粗糠柴(Mallotus philippinensis)的己烷溶解部分中分离得到3个新的查耳酮衍生物(1～3),并研究了其对活性巨噬细胞产生NO的抑制作用。取自然干燥蒴果(500g),用丙酮室温提取,提取物(53.4g)混悬于水,用正己烷、乙酸乙酯和正丁醇依次萃取。正己烷部分上 Three new chalcone derivatives (1–3) were isolated from the hexane-soluble fraction of Mallotus philippinensis, which was traditionally used as an insect repellent and cathartic, and its macrophage activity was studied. The cells produce NO inhibition. Naturally dried pods (500 g) were taken and extracted with acetone at room temperature. The extract (53.4 g) was suspended in water and extracted sequentially with n-hexane, ethyl acetate and n-butanol. On the hexane section