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目的:探讨米非司酮治疗子宫肌瘤的临床疗效。方法:将62例围绝经期子宫肌瘤患者自月经第1天睡前口服米非司酮10mg,1次/d,连服3个月,彩超监测治疗前后子宫及子宫肌瘤的体积变化,治疗前后肝肾功能、血红蛋白量、治疗副反应及生活质量。结果:经米非司酮治疗后,用药过程中均闭经,贫血得以纠正,围绝经期可致绝经。子宫平均体积及肌瘤平均体积较治疗前显著缩小,提高生活质量。结论:米非司酮治疗子宫肌瘤有临床应用价值。
Objective: To investigate the clinical efficacy of mifepristone in the treatment of uterine fibroids. Methods: 62 cases of uterine fibroids in menopausal women from the first day before bedtime oral administration of mifepristone 10mg, 1 / d, and even for 3 months, color Doppler ultrasound monitoring before and after treatment of uterine and uterine fibroids volume changes, Liver and kidney function, hemoglobin, side effects and quality of life before and after treatment. Results: After mifepristone treatment, amenorrhea during menstruation, anemia can be corrected, perimenopause can cause menopause. The average size of the uterus and the average volume of fibroids significantly reduced compared with before treatment, improve quality of life. Conclusion: The treatment of uterine fibroids with mifepristone has clinical value.