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对盆腔肿块患者良恶性病变的鉴别是妇科常遇到的难题。血清CA-125水平的测定已成为评价卵巢癌相对有效的免疫诊断方法。约有2/3的卵巢癌患者的这种抗原的血清水平升高。应用单克隆抗体(MoAb)发展的血清锰过氧歧化酶(Mn-SOD)特异性的酶联免疫吸附试验(ELISA)评价MnSOD在卵巢癌患者中的临床意义。正常血清标本从195例男性和207例女性健康献血者中获得,同时也从术前或放疗前1周内的119例盆腔肿块和妇科恶性肿瘤中取得标本,其中包括
The identification of benign and malignant lesions in pelvic mass is often encountered in gynecological problems. Determination of serum CA-125 level has become a relatively effective immunoassay for the evaluation of ovarian cancer. About two-thirds of ovarian cancer patients have elevated serum levels of this antigen. To evaluate the clinical significance of MnSOD in patients with ovarian cancer by using enzyme-linked immunosorbent assay (ELISA) specific for serum manganese superoxide dismutase (Mn-SOD) developed by monoclonal antibody (MoAb). Normal serum samples were obtained from 195 male and 207 female healthy blood donors, as well as from 119 pelvic masses and gynecological malignancies preoperatively or within 1 week prior to radiotherapy, including