内镜下卢戈尔液染色在早期食管癌及癌前病变诊断中的应用

来源 :临床合理用药杂志 | 被引量 : 0次 | 上传用户:hellosunday
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目的分析内镜下卢戈尔液染色在早期食管癌及癌前病变诊断中的应用。方法选取行胃镜检查的患者80例,用2.0%卢戈尔液10ml对其行内镜下食管黏膜染色,视染色情况进行活组织病理检查,将病理结果与染色结果进行对比分析、判断,了解卢戈尔液染色的准确率与符合率。结果 80例患者中经卢戈尔液染色后诊断食管癌19例,癌前病变22例,主要表现为卢戈尔液不染或淡染,诊断食管癌与癌前病变准确率为62.12%(41/66);不染的食管癌和食管重度不典型增生诊断准确率95.24%(20/21)。结论内镜下卢戈尔液染色用于早期食管癌及癌前病变诊断等降低了漏诊率及误诊率,具有重要临床价值,值得基层医院推广应用。 Objective To analyze the application of Lugar solution endoscopy in the diagnosis of early esophageal cancer and precancerous lesions. Methods Eighty patients underwent gastroscopy were enrolled in this study. Endoscopic esophageal mucosa staining was performed with 10 ml 2.0% Lugol’s solution, and biopsy was performed according to the staining. The pathological results were compared with the staining results to determine and understand The accuracy and coincidence rate of Lugar solution staining. Results In 80 patients, 19 cases of esophageal cancer and 22 cases of precancerous lesions were diagnosed by Lugol’s solution. The accuracy of the diagnosis of esophageal cancer and precancerous lesions was 62.12% 41/66). The diagnostic accuracy of non-stained esophageal cancer and esophageal atypical hyperplasia was 95.24% (20/21). Conclusion Lugol’s endoscopic staining for the diagnosis of early esophageal cancer and precancerous lesions reduces the rate of missed diagnosis and misdiagnosis, which has important clinical value and is worthy of promotion and application in primary hospitals.
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