论文部分内容阅读
目的:调查鸦胆子油乳注射液在某院肿瘤内科的临床使用情况,评价其合理性,以促进临床合理用药。方法:选取肿瘤内科2012年7~12月出院的所有使用过鸦胆子油乳注射液的病例共107例,时其使用情况进行分类调查、统计及分析。结果:107例中有69例(64.4%)患者的使用符合说明书适应证,另外38例(35.6%)与说明书适应证不符;用法、剂量及溶媒均符合说明书要求,平均使用时间为(14.5±10.89)d;发生不良反应4例(3.7%),部分病例使用后出现肝功能异常。结论:某院肿瘤内科使用鸦胆子油乳注射液的用法用量及溶媒等方面符合药品说明书及相关规定,但还存在与说明书规定适应证不符的现象,给药剂量个体化不够,鸦胆子油乳注射液说明书有待完善。
Objective: To investigate the clinical use of Brucea javanica oil injection in the medical oncology in a hospital and to evaluate the rationality of Brucea javanica oil emulsion injection in order to promote clinical rational use of drug. Methods: A total of 107 cases of Brucea javanica Injection who were discharged from hospital from July to December in 2012 were selected. Their conditions of use were classified, investigated and statistically analyzed. Results: The application of 69 patients (64.4%) in 107 cases was in compliance with the instructions and the other 38 cases (35.6%) were inconsistent with the indications. The usage, dosage and vehicle were in accordance with the instructions and the average usage time was (14.5 ± 10.89) d; adverse reactions in 4 cases (3.7%), some cases of liver dysfunction after use. Conclusion: The usage of Brucea javanica oil injection in the department of oncology of a hospital and the solvent are in accordance with the drug specification and relevant regulations, but there are still some inconsistencies with the indications prescribed in the instruction manual. The dosage of the Brucea javanica oil emulsion is not enough, Injection instructions to be perfected.