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目的探讨肝叶切除并肝门胆管癌根治术治疗肝门胆管癌的疗效。方法选择2008年4月至2011年4月行肝门胆管癌根治术的患者96例,依据治疗方案分为两组,对照组给予肿瘤局部切除术,实验组给予联合肝叶切除术,随访观察患者术后根治性切除率、术后并发症及生存率,评价治疗效果。结果实验组术后根治性切除率为80.39%,高于对照组的46.67%,差异有统计学意义(P<0.05)。实验组术后3年生存率为29.41%,高于对照组的11.11%,差异有统计学意义(P<0.05)。结论肝叶切除并肝门胆管癌根治术可显著提高肝门胆管癌患者根治性切除率,改善其生活质量,延长生存期,疗效显著。
Objective To investigate the curative effect of hepatic lobectomy and radical resection of hilar cholangiocarcinoma for the treatment of hilar cholangiocarcinoma. Methods Ninety-six patients undergoing radical hepatic hilar cholangiocarcinoma between April 2008 and April 2011 were selected and divided into two groups according to the treatment plan. The control group was given local tumor resection, and the experimental group was given combined hepatectomy. Follow-up observation Radical resection rate, postoperative complications, and survival rate were evaluated in patients after surgery. Results The radical resection rate in the experimental group was 80.39%, which was higher than that in the control group (46.67%). The difference was statistically significant (P<0.05). The 3-year survival rate in the experimental group was 29.41%, which was 11.11% higher than that in the control group. The difference was statistically significant (P<0.05). Conclusion Liver lobectomy and radical resection of hilar cholangiocarcinoma can significantly improve the radical resection rate, improve the quality of life, and prolong the survival time of patients with hepatic hilar cholangiocarcinoma. The curative effect is significant.