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凝血酶原是由肝脏合成的依赖维生素Ｋ的凝血因子。异常凝血酶原（ＡｂｎｏｒｍａｌＰｒｏｔｈｒｏｍｂｉｎ，ＡＰＴ）和凝血酶原的化学结构极其相似，区别在于：ＡＰＴ分子氨基端的特定位置上的谷氨酸残基未经羧基化，因而缺乏结合钙离子的结构基础，在一般凝血试验中无凝...
Prothrombin is a vitamin K-dependent coagulation factor synthesized by the liver. The chemical structure of Abnormal Prothrombin (APT) and prothrombin is very similar except that the glutamate residue at a specific amino-terminal position of the APT molecule is not carboxylated and therefore lacks the structural basis for the binding of calcium ions. General clotting test without coagulation ...